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Moses Waldron opened the first store in Bishop’s Mills. He was instrumental in bringing telegraph services to the hamlet. Upon his death in 1860 his widow married George Ferguson and continued to run the business with his nephew Jack. The extensive mercantile business stocked nails, glass, tools, dry goods, boots, shoes, hats and gloves as well as staples such as coffee, tea, sugar, salt and tabacco. Local produce such as cheese, butter, and eggs would be shipped by wagon to Oxford Station and then by rail on to Bedell and then Montreal. The building was used as a store until 2002. It has most recently served as the home of the Bishops Mills Natural History Centre.